MDM2 Inhibition Predictor | AI-Powered Drug Discovery

🔬 Predict MDM2 Inhibition

Enter SMILES String

Enter Multiple SMILES (one per line)

Click on an example to try it:

Ethanol

CCO

Acetic Acid

CC(=O)O

Benzene

c1ccccc1

Nicotine

CN1CCC[C@H]1C2=CN=CC=C2

Ibuprofen

CC(C)CC1=CC=C(C=C1)C(C)C(=O)O

Benzoic Acid

C1=CC=C(C=C1)C(=O)O

🤖 AI is analyzing your molecule(s)...

🚀 Advanced AI Features

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Graph Neural Networks

Analyzes molecular structure as graphs to understand atom-bond relationships

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Adversarial Training

Enhanced robustness through domain adversarial learning techniques

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Evolutionary Optimization

Automatically selects optimal molecular features using genetic algorithms

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Confidence Scoring

Provides reliability estimates for each prediction

🎯 What is MDM2?

MDM2 (Mouse Double Minute 2) is a crucial protein that regulates p53, known as the "guardian of the genome." In cancer cells, MDM2 often blocks p53's tumor suppressor functions. MDM2 inhibitors can restore p53 activity, making them promising anti-cancer therapeutics. Our AI model predicts which molecules are likely to inhibit MDM2, accelerating drug discovery.